Available technologies, Clean Technologies, Electrical and Electronic components, Engineering, Environement, Healthcare, Life Sciences, Medical devices, Medical Hardware, Optical devices


A very powerful and low cost technology for detecting ammonia in biomedical and industrial applications.

Ammonia monitoring market opportunity

  • NH3 is one of the largest-volume synthetic chemicals produced in the world (~200 M metric tons in 2018)
  • 88% of NH3 production is used for fertilizers
  • Other NH3 sources include automotive and mining industries, livestock, food and pulp & paper industries, refrigeration, oil industry
  • Gas sensors global market = $1.3 B by 2023
  • NH3 segment = $73.3 M in 2023
  • NH3 = 75% of gas sensor market for water & wastewater treatment ($70.4 M in 2023)

Biomedical unmet need for NH3 breath analyzer

    • NH3 is a by-product of protein metabolism
    • Unmet need for NH3 breath analyzer in point-of-care diagnostic of liver/kidney diseases, H. pylori infection, stomach/lung cancers
    • Global market for sensors in point-of-care applications = $7.67 billion in 2023

A new lab-on-chip device for ammonia sensing

  • Modification of PDMS (polydimethylsiloxane) composite film by ninhydrin integration
  • Lab-on-chip device developed by integrating the ninhydrin-PDMS into a microfluidic device
  • Optical specific detection of NxHy groups (NH3 and amino acids)
  • Integrated light emitting diode and photoresistor to measure changes in absorption
  • Technology developed by Dr. Muthu Packirisamy (Department of Mechanical and Industrial Engineering, Concordia University)
  • Development stage: TLR4-5
  • Patent status: PCT application in March 2019

Multiple competitive advantages

  • Miniaturization for integration in wearable devices (emerging market)
  • Portable, small size, low weight
  • Low manufacturing cost
  • Disposable (or not)
  • USB connection or wireless options
  • High sensitivity (adjustable to ppb or ppm range)
  • High signal to noise ratio
  • Ammonia specific detection

Partnering opportunity

  • Searching for industrial partners to develop ammonia sensing products according to specific market needs
  • Technology available for in-licensing


If you are interested by this technology, please contact :

Sébastien Chaffre, Director Business Development, Life Sciences
schaffre@aligo.ca, (438) 728-7580


Concordia University

Main inventor

Photo Muthukumaran Packirisamy

Dr. Muthukumaran Packirisamy

Professor, Mechanical, Industrial and Aerospace Engineering
Concordia Institute of Aerospace Design & Innovation

Dr. M. Packirisamy, a Professor and Concordia Research Chair at the Department of Mechanical Engineering at Concordia University, Director of Micro-Nano-Bio Integration Center and Optical Bio Microsystems Lab, a co-founder of the start-up company on 3D Manufacturing, is an academician of Canada, a member of Royal Society of Canada and recipient of Fellows of Canadian Academy of Engineering, Engineering Institute of Canada, American Society of Mechanical Engineers, Institution of Engineers India, Canadian Society for Mechanical Engineering and I.W.Smith award, Concordia University Research Fellow, Petro Canada Young Innovator Award and ENCS Young Research Achievement Award. As an author of around 430 articles published in journals and conferences, 40 invited talks, 20 inventions, he has supervised more than 170 personnel including 12 Research Associates, 31 PhDs, 51 Masters and 69 UG students and obtained grants around $15 Million. He is a world leader on multi-disciplinary area of micro-nano-integrated-Lab-on-Chips for applications in life sciences.

External links

ipsum tempus leo consequat. felis lectus elementum leo. non